Administration: Methio-Form Chewable Tablets may be fed free choice, from the hand or maybe crumbled and mixed into the food. Dosing one time each day is appropriate, but daily doses may be administered in 2 or 3 divide, doses if more convenient or in rare cases where animals may vomit a single daily dose. For urinary acidification in cats and dogs and prevention of struvite urolithiasis urinary pH should be reduced to approximately 6.0 – 6.6 and maintained in this range. Monitoring the pH of freshly voided urine may be advisable. Dosage: Daily dosages vary with diets and amount of acidification needed. After dosages have been determined, they may be used continuously. Cats: The usual daily dose is 2.5 to 5.0 mEq 188-375 mg/kg body weight or 1/2 to one tablet per 1 to 1.5 kg. 2.5 to 3 lb body weight. Average size adult cats normally should receive 1 1/2 to 3 tablets 10-20 mEq daily. Dogs: The usual daily dose is 2 to 4 mEq 150-300 mg/kg body weight. Small breeds – 7 kg 15 lb or under, / to 4 tablets. Medium Breeds – 7 to 15 kg 15-33 lb, 2 to 7 tablets. Large Breeds -15-30 kg 33-66 lb, 4 to 13 tablets. Note: Methio-Form tablets can be crumbled and sprinkled on the animal&rsquos food. A level teaspoonful of a crumbled tablet contains 746 mg 10.0 mEq of or-methionine.Contraindications: Do not administer to animals with severe liver, kidney or pancreatic disease, or those which are acidotic due to conditions such as uncontrolled diabetes mellitus or urinary obstruction. Warning: Methio-Form is extremely palatable to dogs and cats and overconsumption of tablets may result if access to open bottles occurs. The effect of overconsumption may be severe and could result in life-threatening metabolic acidosis if veterinary treatment is not initiated. Also, excess consumption of methionine may result in the production of methyl mercaptan methanethiol which may be toxic. In animals with healthy livers, metabolites of methionine are converted to nontoxic substances. Generally, methionine in the diet at twice the required level is well tolerated, but at a threefold or above level toxicosis often results. Precautions: In rare cases animals may experience gastrointestinal disturbance. In those cases, administer during feeding or in two to three divided doses. Caution should be advised against overdosing animals to avoid chronic over acidification which could lead to potential problems such as acidosis, potassium wasting, osteoporosis, Heinz body formation, and possible precipitation of non-struvite minerals in the urine. Cats have been frequently poisoned by ingesting numerous tablets from bottles which were left open. The intoxication resulting from accidental over consumption is primarily an acidemia. The recommended treatments for the acidosis include parenteral solutions, such as saline-bicarbonate with dextrose, lactated Ringer, lactate, bicarbonate, or Darrows or Butlers for acidosis. Sodium bicarbonate administered orally may be helpful unless the animal has been vomiting frequently. Avoid the use of ammonium salts of solutions. Adult cats ingesting 20 Methio-Form tablets at one time may be expected to become nonlethally intoxicated, but cats ingesting 40 or more tablets will probably die without treatment. Methio Form Chew Tabs 500mg 500 count bottle. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.