Benefits: * Regu-Mate effectively suppresses estrus in 95 percent of mares after 3 days of treatment. * When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally.* Regu-Mate can help alleviate moodiness and temperament changes associated with estrus. * It&rsquos easy to administer &ndash orally or top-dressed on grain.ACTIONS: Regu-Mate altrenogest Solution 0.22% produces a progestational effect in mares. INDICATIONS: Regu-Mate® altrenogest Solution 0.22% is indicated to suppress estrus in mares. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Suppression of estrus will also facilitate management of prolonged estrus conditions. Suppression of estrus may be used to facilitate scheduled breeding during the physiological breeding season. CONTRAINDICATIONS: Regu-Mate® altrenogest Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation i.e., acute, subacute, or chronic endometritis. Natural or synthetic gestagen therapy may exacerbate existing low-grade or moldering uterine inflammation into a fulminating uterine infection in some instances. Regu Mate Dosing Device with Strap Cap and Extra O-Rings. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.