Dosage and Administration:It is important to follow your Veterinarian's prescription instructions for your pet.The normal dose in dogs is 20 to 50 mg/kg every 8 hours for 3-6 weeks depending on the severity of the condition as well as the response of the animal under treatment. The maximum permissible dosage of sulfasalazine is 1 g per dose. Administer Sulfasalazine after meals, and get the pet to swallow the tablets in whole.In cats, a daily dose of 10 to 20 mg/kg is suggested, which should be used with caution as felines are generally responsive to salicylates.Possible Side Effects: Skin rash, pruritus, urticaria, Heinz body anemia, blood dyscrasias, hepatitis, renal toxicity, dry eye, low sperm count etc. Non-enteric-coated forms of sulfasalazine might result in gastrointestinal disturbances along with or without anorexia, nausea or diarrhea.Sulfasalazine is not safe to use in pregnant animals or those, which are allergic to the drug, sulfonamides, or salicylates. Do not treat animals with intestinal or urinary tract blockages and conditions like porphyria with this drug. Administer this drug with caution in pets with fever, jaundice, renal or liver conditions and blood dyscrasias as they are high-risk groups. Your Veterinarian may conduct periodic urine analysis and liver function tests for animals undergoing Sulfasalazine therapy. Possible Drug Interactions:It can interact with many medications like Digoxin, Folic acid and Sulfonylureas, which can result in complications like low absorption and defective hepatic metabolism. Sulfasalazine Tablets 500mg 100 Count Bottle. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.