Dosage:The dosage is 1 mL injected subcutaneously or intramuscularly. Open the syringe by twisting or tapping the cap against a hard surface to break the heat weld. Prepare the vaccine by injecting the diluent into the vial containing the desiccated vaccine cake. Shake well. Withdraw entire contents into the syringe. Thoroughly prepare injection site with antiseptic. Inject 1 mL subcutaneously or intramuscularly. Puppies 9 weeks or younger: Vaccinate healthy puppies at 3-4 week intervals until 16 weeks of age for at least 3 doses. Puppies over 9 weeks and adults: Give a minimum of 2 doses at 3-4 week intervals. Annual revaccination with a single dose is recommended. Precautions: Do not vaccinate pregnant animals. Do not use in ferrets or mink. Protective immunity may not be completely established in all puppies vaccinated at less than 16 weeks of age because of maternal antibody interference. Only vaccinate healthy animals. Animals incubating any disease or stressed due to shipping, malnutrition, or parasitism may not achieve or maintain an adequate immune response. Burn containers and unused contents. Although rare, severe allergic reactions anaphylactoid may occur that require immediate veterinary care. Antidote: Epinephrine Frequently Asked Questions: 1. Why do I need to vaccinate my 9 week old puppy three times? Puppies need multiple vaccinations that are age appropriate to be properly vaccinated and prevent vaccine failure from maternal antibody interference. Be sure your 9-week old puppy receives a vaccination every 2-3 weeks until they are 16 weeks of age. 2. Do I need to vaccinate my dog annually? Yes. All Solo-Jec® vaccines are all USDA-labeled and recommended for annual vaccination. 5 Way Canine Vaccines Duramune Max 5 x 25 Doses. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.