Generic Names:Gentamicin sulfate + Betamethasone valerate + Clotrimazole OintmentContains:Each gram of Otibiotic Ointment gentamicin-betamethasone-clotrimazole ointment contains gentamicin sulfate USP equivalent to 3 mg gentamicin base betamethasone valerate, USP equivalent to 1 mg betamethasone and 10 mg clotrimazole, USP in a mineral oil-based system containing a plasticized hydrocarbon gel. Dosage and Administration:The external ear should be thoroughly cleaned and dried before treatment. Remove foreign material, debris, crusted exudates, etc., with suitable non-irritating solutions. Excessive hair should be clipped from the treatment area. After verifying that the eardrum is intact, instill 4 drops 2 drops from the 215 g bottle of Otibiotic Ointment gentamicin-betamethasone-clotrimazole ointment twice daily into the ear canal of dogs weighing less than 30 lbs. Instill 8 drops 4 drops from the 215 g bottle twice daily into the ear canal of dogs weighing 30 lbs or more. Therapy should continue for 7 consecutive daysCautions: for use in dogs not for use in dogs with ruptured ear drums not for use in pregnant pets not for use in pet's that have had an allergic reaction to aminoglycoside antibiotic gentamicin sulfate, an adrenocorticoid betamethasone and an antifungal agent clotrimazole or any of the generic products Warnings: The use of Otibiotic Ointment gentamicin-betamethasone-clotrimazole ointment has been associated with deafness or partial hearing loss in a small number of sensitive dogs eg. geriatric. The hearing deficit is usually temporary. If hearing or vestibular dysfunction is noted during the course of treatment, discontinue use of Otibiotic Ointment gentamicin-betamethasone-clotrimazole ointment immediately and flush the ear canal thoroughly with a non-ototoxic solution. Corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Other congenital anomalies including deformed forelegs, phocomelia, and anasarca have been reported in offspring of dogs which received corticosteroids during pregnancy. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Precautions: Identification of infecting organisms should be made either by microscopic roll smear evaluation or by culture as appropriate. Antibiotic susceptibility of the pathogenic organisms should be determined prior to use of this preparation. If overgrowth of nonsusceptible bacteria, fungi, or yeasts occur, or if hypersensitivity develops, treatment should be discontinued and appropriate therapy instituted. Administration of recommended doses of Otibiotic Ointment gentamicin-betamethasone-clotrimazole ointment beyond 7 days may result in delayed wound healing. Avoid ingestion. Adverse systemic reactions have been observed following the oral ingestion of some topical corticosteroid preparations. Patients should be closely observed for the usual signs of adrenocorticoid overdosage which include sodium retention, potassium loss, fluid retention, weight gain, polydipsia and/or polyuria. Prolonged use or overdosage may produce adverse immunosuppressive effects. Use of corticosteroids, depending on dose, duration, and specific steroid, may result in endogenous steroid production inhibition following drug withdrawal. In patients presently receiving or recently withdrawn from corticosteroid treatments, therapy with a rapidly acting corticosteroid should be considered in especially stressful situations. Before instilling any medication into the ear, examine the external ear canal thoroughly to be certain the tympanic membrane is not ruptured in order to avoid the possibility of transmitting infection to the middle ear as well as damaging the cochlea or vestibular apparatus from prolonged contact. Otibiotic Ointment by Butler Schien 215 gm. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.