Benefits: * Broad-spectrum antibiotic treats a range of bacterial and protozoal infections * Used for respiratory, urinary tract, skin or gastrointestinal infections and other conditions * Trimethoprim works with sulfamethoxazole for better effectiveness Dosage and Administration:Follow your Veterinarian's prescription instructions for your pet. Always have plenty of drinking water available – your pet should not become dehydrated while taking SMZ-TMP Shake liquid forms well before use. Give by mouth. This medication may be given with food. If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once. Cautions:Not for use in animals who are hypersensitive allergic to it or other sulfa medications. Not for use in pregnant or lactating animals female animals nursing their young unless benefits outweigh the risks. Not for use in animals with dehydration bladder or kidney stones or severe liver or kidney disease. Use with caution in animals with blood cell abnormalities such as anemia. This medication should only be given to the pet for which it was prescribed. Consult your veterinarian before using trimethoprim/sulfa with other medications, including vitamins and supplements, methotrexate, warfarin, phenylbutazone, thiazide, diuretics, salicylates aspirin, probenecid, antacids, or phenytoin, since interactions may occur. Possible Side Effects:It is common to find sulfa crystals in the animal's urine during a urinalysis a test on the urine, which does not pose a problem in animals that remain well hydrated. Less common, keratoconjunctivitis sicca KCS, dry eye may occur with long-term use of trimethoprim/sulfa. Stop giving the medication and consult your veterinarian if your pet experiences discharge from the eye, redness of the eye, squinting, or other signs related to the eye. Other less common side effects in dogs include anemia resulting in pale gums and tiredness low platelets resulting in bleeding tendencies fever loss of appetite, vomiting diarrhea joint inflammation arthritis resulting in lameness kidney damage resulting in increased thirst and urination liver damage and skin rashes with possible sensitivity to sunlight. Stop giving the medication and consult your veterinarian if your pet experiences any of these signs. Dogs can develop hypothyroidism with long-term use. Cats will often drool excessively if allowed to taste the medication. Side effects in cats may include loss of appetite, low white blood cell counts and anemia resulting in pale gums and tiredness. Consult your veterinarian if your pet experiences any of these side effects. SMZ/TMP 960mg Double Strength 500 Count Bottle. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.