Benefits: Clomicalm is used to calm dogs Training becomes easier Positive behaviors can be taughtInappropriate barking or destructive behavior, as well as inappropriate elimination urination or defecation may be alleviated by the use of Clomicalm Tablets in conjunction with behavior modification. The use of Clomicalm Tablets should not replace appropriate behavioral and environmental management but should be used to facilitate a comprehensive behavior management program. Dosage and Administration:The recommended daily dose of Clomicalm Tablets is 2 to 4 mg/kg/day 0.9 -1.8 mg/lb/day.Please follow your Veterinarians dosage and administrtion instructions.Clomicalm can be administered as a single daily dose or divided twice daily based on patient response and/or tolerance of the side effects. Sometimes it may beadministered as divided doses to minimize side effects by permitting tolerance to side effects to develop or allowing the patient time to adapt if tolerance does not develop. To reduce the incidence of vomiting that may be experienced by some dogs, Clomicalm Tablets may be given with a small amount of foodPrecautions: Clomicalm Tablets are contraindicated in dogs with known hypersensitivity to clomipramine or other tricyclic antidepressants. Clomicalm Tablets should not be used in male breeding dogs. Testicular hypoplasia was seen in dogs treated for 1 year at 12.5 times the maximum daily dose. Clomicalm Tablets should not be given in combination, or within 14 days before or after treatment with a monoamine oxidase inhibitor [e.g. selegiline hydrochloride L-deprenyl,amitraz]. Clomicalm Tablets are contraindicated for use in dogs with a history of seizures or concomitantly with drugs which lower the seizure threshold.General: Clomicalm Tablets are not recommended for other behavior problems, such as aggression. Periodic reassessment of hematological and serum biochemical data during the administration of this medication is advised. Human Warnings: Not for use in humans. Keep out of reach of children. In case of accidental ingestion seek medical attention immediately. In children, accidental ingestion should be regarded as serious.There is no specific antidote for clomipramine. Overdose in humans causes anticholinergic effects including effects on the central nervous e.g., convulsions and cardiovascular e.g., arrhythmia, tachycardia systems. People with known hypersensitivity to clomipramine should administer the product with caution. Drug Interactions: It is important to discuss with your Veterinarian any other medications, prescription or over the counter medications/vitamins your pet may be taking.Discuss with your veterinarian if your pet takesphenobarbita,tricyclic antidepressants. Caution is advised in using clomipramine with anticholinergic or sympathomimetic drugs or with other CNS-active drugs, including general anesthetics and neuroleptics. Prior to elective surgery with general anesthetics, clomipramine should be discontinued for as long as clinically feasible.Don&rsquot use Clomipramine if your pet has taking a monoamine oxidase inhibitor MAOI such as Anipryl, or selegiline, or has been using a Preventic Collar in the last 14 days. Clomipramine may increase the effects of other drugs and may cause drowsiness. Pet's who have otherIllnesses: Use with caution in dogs with cardiovascular disease.Because of its anticholinergic properties, clomipramine should be used with caution in patients with increased intraocular pressure, a history of narrow angle glaucoma, urinary retention or reduced gastrointestinal motility. Because clomipramine is principally metabolized in the liver, caution is advised in using this medication in the presence of preexisting liver disease. Clomicalm 20mg 30 Count Bottle. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.