Benefits: The #1 veterinarian recommended joint health supplement brand Broad spectrum joint support in a tasty powder Contains exclusive trademarked ingredients: FCHG49®;Glucosamine, TRH122®;Chondroitin Sulfate, and NMX1000®;Avocado/Soybean Unsaponifiables (ASU); and Methylsulfonylmethane (MSM) ASU complements the effects of Glucosamine and Chondroitin Sulfate What is ASU? ASU stands for avocado/soybean unsaponifiables, derived from avocados and soybeans. Studies using cartilage cells have shown that it lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the glucosamine and chondroitin sulfate in Cosequin®ASU. The glucosamine in Cosequin ASU is synergistic with chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Having ASU in the Cosequin ASU formula is especially beneficial as NMX1000® avocado/soybean unsaponifiables, FCHG49® glucosamine hydrochloride and TRH122® chondroitin sulfate together were shown in cell studies to be more effective than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. Why is MSM included in the formula? Although clinical data on MSM is limited, many veterinarians and trainers recommend the use of MSM in the management of joint health. MSM is an organic source of sulfur, a compound used by cartilage. Cosequin ASU provides a joint health supplement formula for those individuals that would like to additionally supplement with high purity MSM. What is meant by broad spectrum? Broad spectrum means that the ingredients support cartilage health via many pathways. As mentioned earlier in this brochure, the ingredients inhibit compounds and enzymes in the joint that contribute to cartilage breakdown while also supporting cartilage production. How is Cosequin®ASU different from other supplements? Cosequin ASU contains the ingredient ASU along with the optimal amounts of glucosamine and chondroitin sulfate that your horse needs. ASU works along with glucosamine and chondroitin sulfate to support your horse's joints. In fact, the combination of glucosamine/ chondroitin sulfate plus ASU has been shown to work better in cartilage cell research than glucosamine/chondroitin sulfate alone. Cosequin ASU has the further addition of high purity MSM. Some veterinarians suggest using MSM to help manage joint health. Are there any safety concerns with Cosequin ASU? Cosequin ASU has been evaluated in a safety study in horses, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Cosequin ASU and any drug or nutritional supplement. Can Cosequin ASU be given to a pregnant mare? No studies have been completed that specifically address the use of Cosequin ASU during pregnancy. Use of Cosequin ASU during pregnancy should be an individual decision made in consultation with your veterinarian. Can Cosequin ASU be used on a competition day? Cosequin ASU contains supplement ingredients for assisting joint health. It is best to check with your appropriate authority regarding its regulations or restrictions on supplement usage. What response should I see in my horse when giving Cosequin ASU? Prior to starting Cosequin ASU, you may have noticed unevenness of gait, reluctance to take or change a lead, or shortness of stride, which may be early indicators of cartilage breakdown. After starting administration with Cosequin ASU, observe your horse closely, and notice whether your horse becomes more comfortable doing those activities he/she seemed reluctant doing or had some trouble doing previously. Changes in your horse's comfort level may occur gradually. Please allow time for your horse to respond. As noted above, it may take 2-4 weeks to see improvement, though some horses may respond sooner. My veterinarian has also recommended an injectable joint product. Why? Cosequin ASU helps to minimize ongoing joint wear and tear by supporting joint cartilage production and by inhibiting enzymes and mediators involved in cartilage breakdown. Horses will usually respond to Cosequin ASU within 2-4 weeks, sooner in some horses. In those cases in which a more immediate response is desired, your veterinarian may initially recommend an injectable product. Cosequin ASU Equine Powder 1300 GM Jar. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.