How does NexGard kill fleas? NexGard contains the ingredient afoxolaner. Afoxolaner kills fleas by over-stimulating their nervous system. How long does it take NexGard to kill fleas? In a study, NexGard killed 100% of fleas within 24 hours.5 Why am I seeing more fleas on my pet after administering NexGard? NexGard stimulates the flea's nervous system, causing them to rise to the top of your dog's haircoat as they die. Does NexGard have an expiration date? Two years from the date of manufacture. You can locate the expiration date on the outside of the package of NexGard. Because NexGard is an oral product, swimming or bathing has no effect on NexGard. Your dog's coat can get wet immediately after taking NexGard. Can I use it if my dog is on medication? In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics including topicals, steroids, nonsteroidal anti-inflammatory drugs NSAIDs, anesthetics, and antihistamines. Is NexGard safe to use on any breed of dog? NexGard is safe and effective in any breed of dog when used as directed. Can I use NexGard if I have already applied another flea and tick control product? In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics including topicals, steroids, nonsteroidal anti-inflammatory drugs NSAIDs, anesthetics, and antihistamines. Can NexGard be used on cats and other pets? No. NexGard should be used on dogs only. Can I administer it more than once a month? Don't re-administer NexGard before the month is through. It keeps working for a full 30 days. How old does my dog need to be in order to take NexGard? NexGard can be used in puppies 8 weeks of age or older and weighing 4 pounds or greater. Are there any side effects of NexGard? NexGard is for dogs only and hasn't been evaluated for use in pregnant, breeding or lactating dogs. Reported side effects include vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. Use with caution in dogs with a history of seizures. IMPORTANT SAFETY INFORMATION: NexGard is for use in dogs only. The most frequently reported adverse reactions include vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. The safe use of NexGard in pregnant, breeding or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. 1. Data on file. Merial, Limited. 2. Vet-dispensed MDI Data. Nexgard 60.1-121 lbs 3 Doses. I do not receive this product or any others in exchange for this article, I do get a commission for readers clicking the buy now links which helps to differ the cost of hosting this blog and I sincerely hope this article site helps you with your search for Vet Approved Rx products.